发明名称 |
METHODS AND APPARATUSES FOR ANALYZING BIOLOGICAL SAMPLES BY MASS SPECTROMETRY |
摘要 |
Methods and apparatuses are disclosed for analyzing proteins and other biological materials and xenobiotics within a sample. A specimen is generated (20), which may include an energy absorbent matrix. The specimen is struck with laser beams (22) such that the specimen releases proteins. The atomic mass of the released proteins over a range of atomic masses is measured (24). An atomic mass window of interest within the range of atomic masses is analyzed (32) to determine the spatial arrangement of specific proteins within the sample, and those specific proteins are identified (34) as a function of the spatial arrangement. By analyzing the proteins, one may monitor and classify disease within a sample (39). |
申请公布号 |
WO03034024(A3) |
申请公布日期 |
2004.01.08 |
申请号 |
WO2002US29531 |
申请日期 |
2002.09.18 |
申请人 |
VANDERBILT UNIVERSITY;CAPRIOLI, RICHARD |
发明人 |
CAPRIOLI, RICHARD |
分类号 |
G01N27/62;G01N27/64;G01N33/68 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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