发明名称 USE OF VASOPEPTIDASE INHIBITORS IN THE TREATMENT OF NEPHROPATHY
摘要 <p>The invention describes the use of vasopeptidase inhibitors of the formula ( I) for the treatment and/or prophylaxis of nephropathy in diabetic or non- diabetic patients, including diabetic or non-diabetic nephropathy, glomerulonephritis, glomerular sclerosis, nephrotic syndome, hypertensive nephrosclerosis, microalbuminuria or end stage renal disease, or insulin resistence or of metabolic diseases associated with advanced glycation end- products, such as diabetic complications, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, myocardial infarction and/or diabetic cardiomyopathy, or atherosclerosis or endothelial dysfunction.</SDO AB></p>
申请公布号 CA2490277(A1) 申请公布日期 2004.01.08
申请号 CA20032490277 申请日期 2003.06.13
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH 发明人 SCHAFER, STEFAN;LINZ, WOLFGANG;BLEICH, MARKUS;HUBER, JOCHEN
分类号 C07D471/04;A61K31/55;A61K38/00;A61P3/08;A61P3/10;A61P9/10;A61P9/14;A61P13/00;A61P13/02;A61P13/12;A61P25/00;A61P27/02;A61P27/12;A61P43/00;(IPC1-7):A61K31/55 主分类号 C07D471/04
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