<p>The present invention is directed toward particles for delivery of epinephri ne to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described herein comprise the bioactive agent epinephrine, or a salt thereof, as a therapeutic agent. The particles are preferably formed by spray drying. Preferably, the particles and the respirable compositions are substantially dry and are substantially free of propellents. In a preferred embodiment, the particles have aerodynamic characteristics that permit targeted delivery of epinephrine to the site(s) of action.</p>
申请公布号
CA2488976(A1)
申请公布日期
2004.01.08
申请号
CA20032488976
申请日期
2003.06.26
申请人
ADVANCED INHALATION RESEARCH, INC.
发明人
EHRICH, ELLIOT;SUMMA, JASON;LI, WEN-I;HRKACH, JEFFREY S.;FU, KAREN;BATYCKY, RICHARD P.;LIPP, MICHAEL M.;CAPONETTI, GIOVANNI;CHILDS, MARIKO;PAN, MEI-LING