ACAT-1 INHIBITOR

摘要

PROBLEM TO BE SOLVED: To provide an acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT-1) inhibitor comprising a phosphonic acid diester derivative. SOLUTION: The ACAT-1 inhibitor comprises the phosphonic acid diester derivative represented by the formula (wherein, R1, R2, R3and R4are each the same or different and denote each a hydrogen atom, a halogen atom or a lower alkyl group; R5denotes a phenyl group or a pyridyl group which may have a lower alkoxy group on the phenyl ring; and R6denotes a lower alkyl group) as an active ingredient. COPYRIGHT: (C)2004,JPO