COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING CANCER VIA MODULATING UBE1L, ISG15 AND/OR UBP43
摘要
Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15 or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer (neoplastic) or pre-cancerous (pre-neoplastic) cells are provided. Methods for the prevention or treatment of cancer via administration of these compositions are also provided.
申请公布号
WO03075844(A3)
申请公布日期
2004.01.08
申请号
WO2003US06905
申请日期
2003.03.05
申请人
TRUSTEES OF DARTMOUTH COLLEGE;UNIVERSITY OF MARYLAND, BALTIMORE;DMITROVSKY, ETHAN;HASSEL, BRET, A.;KITAREEWAN, SUTISAK;PITHA-ROWE, IAN
发明人
DMITROVSKY, ETHAN;HASSEL, BRET, A.;KITAREEWAN, SUTISAK;PITHA-ROWE, IAN