| 发明名称 |
METHODS AND COMPOSITIONS FOR INHIBITION OF MULTI-DRUG RESISTANCE BY HYALURONAN OLIGOMERS |
| 摘要 |
<p>Pharmaceutical compositions and methods for sensitizing multi-drug resistant cancer or radiation resistant cancer cells to chemotherapeutic agents are provided. Compositions include ligands of hyaluronan receptors, including glycosaminoglycans such as hyaluronan oligomers and derivatives of these oligomers, hyaluronan binding proteins, and antibodies specific for hyaluronan receptors.</p> |
| 申请公布号 |
WO2004003545(A1) |
申请公布日期 |
2004.01.08 |
| 申请号 |
WO2003US20918 |
申请日期 |
2003.07.01 |
| 申请人 |
TUFTS UNIVERSITY;TOOLE, BRYAN, P. |
发明人 |
TOOLE, BRYAN, P. |
| 分类号 |
A61K31/17;A61K31/337;A61K31/475;A61K31/519;A61K31/704;A61K31/726;A61K31/728;A61K38/13;A61K45/00;A61K45/06;A61P31/04;A61P35/00;A61P35/02;A61P43/00;C12Q1/02;G01N33/15;G01N33/50;(IPC1-7):G01N33/00;G01N33/48;C12Q1/00;G01N33/567;G01N33/574;A61K31/00;A61K38/00;A61K38/28;A01N61/00;A01N37/18;G01N33/53 |
主分类号 |
A61K31/17 |
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