发明名称 |
Antisense modulation of cyclin-dependent kinase 4 expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of cyclin-dependent kinase 4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding cyclin-dependent kinase 4. Methods of using these compounds for modulation of cyclin-dependent kinase 4 expression and for treatment of diseases associated with expression of cyclin-dependent kinase 4 are provided.
|
申请公布号 |
US2004005567(A1) |
申请公布日期 |
2004.01.08 |
申请号 |
US20020188779 |
申请日期 |
2002.07.02 |
申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
DEAN NICHOLAS M.;FREIER SUSAN M.;DOBIE KENNETH W. |
分类号 |
A61K38/00;A61K48/00;C07H21/04;C12N15/113;C12Q1/68;(IPC1-7):A61K48/00;C12N5/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|