| 发明名称 |
METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS |
| 摘要 |
<p>The present invention is to prepare efficiently 2'-amino-5'-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis, which is a starting material for irinotecan hydrochloride and various kinds of camptothecin derivatives, and to provide stably CPT and its derivatives.</p> |
| 申请公布号 |
EP1378505(A1) |
申请公布日期 |
2004.01.07 |
| 申请号 |
EP20020703874 |
申请日期 |
2002.02.21 |
| 申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
OGAWA, TAKANORI;NISHIYAMA, HIROYUKI;UCHIDA, MIYUKI;SAWADA, SEIGO |
| 分类号 |
C07C221/00;C07C205/22;C07C205/37;C07C205/44;C07C205/45;C07C225/22;C07D213/64;C07D491/04;C07D491/14;C07D491/147;C07D491/22;(IPC1-7):C07C221/00 |
主分类号 |
C07C221/00 |
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