High activity ruthenium or osmium metal carbene complexes for olefin metathesis reactions and synthesis and application thereof

摘要

A method of preparing a catalyst of the formula comprising: reacting a compound of the formula (XX<1>MLnL<1>m)p with a phosphorane of the formula wherein: M is Os or Ru; R and R<1> are either the same or different and are (a) hydrogen, (b) a group selected from C2-C20 alkenyl, C2-C20 alkynyl, C1-C20 alkyl, aryl, C1-C20 carboxylate, C2-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthio, C1-C20 alkylsulfonyl, or C1-C20 alkylsulfinyl, or (c) one of the groups listed in (b) substituted with C1-C5 alkyl, halogen, C1-C5 alkoxy, unsubstituted phenyl, halogen substituted phenyl, C1-C5 alkyl substituted phenyl, or C1-C5 alkoxy substituted phenyl; R<4>, R<5>, and R<6> are either the same or different and are each unsubstituted or substituted hydrocarbon wherein the hydrocarbon is selected from the group consisting of aryl, C1-C6 alkyl, C1-C6 alkoxy, and phenoxy and the hydrocarbon substitution is selected from the group consisting of halogen, C1-C3 alkyl, C1-C3 alkoxy, unsubstituted phenyl, halogen substituted phenyl, C1-C5 alkyl substituted phenyl, and C1-C5 alkoxy substituted phenyl; X and X<1> are either the same or different and are any anionic ligand; L is any neutral electron donor; L<1> is a trialkylphosphine ligand where at least one of the alkyl groups is a secondary alkyl or a cycloalkyl; n and m are independently 0-4, provided n+m=2, 3 or 4; and p is an integer equal to or greater than 1.