发明名称 |
Methods of ranking oligonucleotides for specificity using wash dissociation histories |
摘要 |
The present invention provides methods and systems, particularly computer systems, for determining the relative specificity with which a particular polynucleotide molecule hybridizes to a polynucleotide probe. For example, the methods and systems of the invention enable a user to compare the specificity with which different polynucleotides hybridize to a given probe and/or rank these polynucleotides according to their specificity to that probe. The methods and systems of the invention also enable a user to compare the specificity with which a particular polynucleotide hybridizes to different probes, and/or rank those different probes according to their specificity for that particular polynucleotide.
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申请公布号 |
US6673536(B1) |
申请公布日期 |
2004.01.06 |
申请号 |
US19990408582 |
申请日期 |
1999.09.29 |
申请人 |
ROSETTA INPHARMATICS LLC. |
发明人 |
STOUGHTON ROLAND;BURCHARD JULJA;FRIEND STEPHEN H. |
分类号 |
C12Q1/68;G06F19/00;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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