发明名称 |
Resolution of DL-racemic mixtures |
摘要 |
The present invention relates to a process for the resolution of DL-racemic mixtures of compounds which crystalize in the form of a conglumerate. Both, the D and L-enantiomers are obtained according to the invention in a industrially feasable process by adding chiral enantioselective polymers to the supersaturated solution of the racemat to inhibit crystalization of one enantiomer. Next a DL-racemic mixture of said compound is suspended in about twice the amount of the crystallized enantiomer. Consequently, the opposite enantiomer could be recovered by said suspension by physical separation.
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申请公布号 |
US6673942(B1) |
申请公布日期 |
2004.01.06 |
申请号 |
US20020181411 |
申请日期 |
2002.07.23 |
申请人 |
DEGUSSA AG;YEDA RESEARCH AND DEVELOPMENT CO., LTD. |
发明人 |
KOTTENHAHN MATTHIAS;KNAUP GUENTER;DRAUZ KARLHEINZ;LAHAV MEIR;ZBAIDA DAVID |
分类号 |
C07B57/00;C07C201/16;C07C205/57;C07C209/88;C07C227/34;C07C229/08;C07C229/22;C07C229/24;C07C231/20;C07C237/06;C07C319/28;C07C323/58;C07D233/54;C07D233/90;(IPC1-7):C07D233/90;C07C205/00;C07C207/00;C07C229/00;C07C321/00 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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