发明名称 |
CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF |
摘要 |
<p>A pyrrolidine derivative, which is an intermediate for a quinuclidine derivate side chain useful as a squalene synthase inhibitor, and producing method thereof are disclosed. A pyrrolidine derivative (X) represented by the following formula (X) (wherein R<1> and R<2> each represents a hydroxy group, C1-6 alkoxy groups or the like; R<3> represents a hydrogen atom, a benzyl group or the like); or a salt thereof or a hydrate thereof: <CHEM></p> |
申请公布号 |
EP1375465(A1) |
申请公布日期 |
2004.01.02 |
申请号 |
EP20020708747 |
申请日期 |
2002.04.01 |
申请人 |
EISAI CO., LTD. |
发明人 |
EGUCHI, YOSHIHITO;CHIBA, KEN-ICHI;GOTO, MASAKI;OBAISHI, HIROSHI;KUBOI, YOSHIKAZU |
分类号 |
A61K31/12;A61K31/235;A61K31/24;A61K31/4402;A61P1/04;A61P1/16;A61P3/10;A61P13/12;A61P17/00;A61P19/02;A61P27/02;A61P29/00;A61P43/00;C07C49/657;C07C49/747;C07C49/753;C07C205/57;C07D207/12;C07D401/04;C07D453/02;(IPC1-7):C07C49/413;C07C49/717;C07C49/517;C07C49/503;A61K31/440;C07D213/16;C07C205/60;C07C69/76;C07C49/84 |
主分类号 |
A61K31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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