| 摘要 |
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment using the subject polymer compositions, and methods of making and using the same. In another part, the present invention includes inclusion complexes of a lapachone or a prodrug thereof and a cyclodextrin, preferably a beta-cyclodextrin, such as hydroxypropyl beta-cyclodextrin, e.g., to improve the solubility of the lapachone or prodrug thereof.
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