发明名称 |
Heteroaromatic derivatives having an inhibitory activity against HIV integrase |
摘要 |
A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is -COOR<A >wherein R<A >is hydrogen or ester residue, -CONR<B>R<C >wherein R<B >and R<C >each is independently hydrogen or amide residue, optionally substituted aryl or optionally substituted heteroaryl; and A<1 >is optionally substituted heteroaryl; provided that a compound wherein Y and/or A<1 >is optionally substituted indol-3-yl is excluded, a tautomer, a prodrug, a pharmaceutically acceptable salt or a hydrate thereof has an inhibitory activity against an integrase.
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申请公布号 |
US2004002485(A1) |
申请公布日期 |
2004.01.01 |
申请号 |
US20030463816 |
申请日期 |
2003.06.18 |
申请人 |
FUJISHITA TOSHIO;YOSHINAGA TOMOKAZU;SATO AKIHIKO |
发明人 |
FUJISHITA TOSHIO;YOSHINAGA TOMOKAZU;SATO AKIHIKO |
分类号 |
C07D207/333;A61K31/427;A61P31/18;C07D231/12;C07D277/24;C07D277/36;C07D333/24;C07D333/34;C07D403/06;(IPC1-7):A61K31/506;A61K31/419;C0743/02;A61K31/41 |
主分类号 |
C07D207/333 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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