发明名称 Heteroaromatic derivatives having an inhibitory activity against HIV integrase
摘要 A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is -COOR<A >wherein R<A >is hydrogen or ester residue, -CONR<B>R<C >wherein R<B >and R<C >each is independently hydrogen or amide residue, optionally substituted aryl or optionally substituted heteroaryl; and A<1 >is optionally substituted heteroaryl; provided that a compound wherein Y and/or A<1 >is optionally substituted indol-3-yl is excluded, a tautomer, a prodrug, a pharmaceutically acceptable salt or a hydrate thereof has an inhibitory activity against an integrase.
申请公布号 US2004002485(A1) 申请公布日期 2004.01.01
申请号 US20030463816 申请日期 2003.06.18
申请人 FUJISHITA TOSHIO;YOSHINAGA TOMOKAZU;SATO AKIHIKO 发明人 FUJISHITA TOSHIO;YOSHINAGA TOMOKAZU;SATO AKIHIKO
分类号 C07D207/333;A61K31/427;A61P31/18;C07D231/12;C07D277/24;C07D277/36;C07D333/24;C07D333/34;C07D403/06;(IPC1-7):A61K31/506;A61K31/419;C0743/02;A61K31/41 主分类号 C07D207/333
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