ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF

摘要

Anthraquinones are described wnicn are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. In vitro or in vivo. The preferred anthraquinones have the formula (I) wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, 15 carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.