发明名称 |
IMMUNOTHERAPY FOR REVERSING IMMUNE SUPPRESSION |
摘要 |
<p>A method for overcoming immune suppression includes the steps of inducing production of naïve T cells and restoring T cell immunity. A method of vaccine immunotherapy includes the steps of inducing production of naïve T cells and exposing the naïve T cells to endogenous or exogenous antigens at an appropriate site. Additionally, a method for unblocking immunization at a regional lymph node includes the steps of promoting differentiation and maturation of immature dendritic cells at a regional lymph node and allowing presentation of processed peptides by resulting mature dendritic cells, thus, for example, exposing tumor peptides to T cells to gain immunization of the T cells. Further, a method of treating cancer and other persistent lesions includes the steps of administering an effective amount of a natural cytokine mixture as an adjuvant to endogenous or exogenous administered antigen to the cancer or other persistent lesions; preferably the natural cytokine mixture is administered in combination with thymosin < ALPHA 1>.</p> |
申请公布号 |
WO03035004(A9) |
申请公布日期 |
2003.12.31 |
申请号 |
WO2002US34361 |
申请日期 |
2002.10.26 |
申请人 |
IMMUNO-RX, INC.;HADDEN, JOHN, W. |
发明人 |
HADDEN, JOHN, W. |
分类号 |
A61K38/00;A61K31/405;A61K31/415;A61K31/4402;A61K31/664;A61K38/19;A61K38/21;A61K38/22;A61K39/00;A61K39/39;A61P31/04;A61P35/00;A61P37/04;A61P43/00;C12N5/08;(IPC1-7):A61K45/00;A01N63/00;A61K47/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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