| 发明名称 |
A PROCESS FOR THE PREPARATION OF OLANZAPINE AND AN INTERMEDIATE THEREFOR |
| 摘要 |
<p>The invention relates to a process for the preparation of olanzapine which process consists in N-methylation of 2-methyl-4-piperazin-1-yl-10H-thieno[2,3-b][1,5]benzodiazepine. The invention relates also to a new intermediate compound, 2-methyl-4-(4-formyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]-benzodiazepine of formula III and a process for the preparation thereof.</p> |
| 申请公布号 |
WO2004000847(A1) |
申请公布日期 |
2003.12.31 |
| 申请号 |
WO2003IB02181 |
申请日期 |
2003.06.10 |
| 申请人 |
ADAMED SP. Z O.O.;MAJKA, ZBIGNIEW;STAWINSKI, TOMASZ;RECHNIO, JUSTYNA;WIECZOREK, MACIEJ |
发明人 |
MAJKA, ZBIGNIEW;STAWINSKI, TOMASZ;RECHNIO, JUSTYNA;WIECZOREK, MACIEJ |
| 分类号 |
C07D495/04;(IPC1-7):C07D495/04 |
主分类号 |
C07D495/04 |
| 代理机构 |
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