| 发明名称 |
MATERIALS AND METHODS FOR INDUCTIONS OF IMMUNE TOLERANCE |
| 摘要 |
The invention provides methods of inducing immune tolerance to target antige ns in individuals seropositive for certain infectious agents by administration of epitopes derived from those infectious agents. Epitopes derived from viruses which carry homologues of interleukin 10 (IL-10) in their genome, such as Epstein Barr virus and cytomegalovirus, are particularly suitable for these purposes. Particularly preferred is the use of the EBV LMP1 protein and epitopes thereof.
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| 申请公布号 |
CA2491196(A1) |
申请公布日期 |
2003.12.31 |
| 申请号 |
CA20032491196 |
申请日期 |
2003.06.24 |
| 申请人 |
UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN |
发明人 |
BARKER, ROBERT NORMAN;VICKERS, MARK ADRIAN;MARSHALL, NEIL ANDREW |
| 分类号 |
C12N15/09;A61K31/7088;A61K35/14;A61K38/00;A61K39/00;A61K48/00;A61P3/10;A61P7/04;A61P7/06;A61P25/28;A61P29/00;A61P37/00;A61P37/08;C07K7/08;C07K14/05;C12Q1/02;G01N33/569;G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
C12N15/09 |
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