发明名称 |
OLIGONUCLEOTIDE INHIBITORS OF MBD2/DNA DEMETHYLASE AND USES THEREOF |
摘要 |
<p>Oligonucleotide inhibitors that inhibit expression of a mammalian MBD2/DNA demethylase (MBD2/dMTase) are provided. The oligonucleotide inhibitors can be used to inhibit the growth or proliferation of tumour cells in vitro and in vivo. The use of the oligonucleotide inhibitors in the treatment of cancer and methods of identifying potential target genes for cancer therapy or diagnosis using the oligonucleotide inhibitors are also provided.</p> |
申请公布号 |
WO2004001027(A1) |
申请公布日期 |
2003.12.31 |
申请号 |
WO2003CA00884 |
申请日期 |
2003.06.20 |
申请人 |
MCGILL UNIVERSITY;SZYF, MOSHE;CAMPBELL, PAUL |
发明人 |
SZYF, MOSHE;CAMPBELL, PAUL |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):C12N9/10;A61K48/00;C12N15/11;C12N15/52;G01N33/50 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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