发明名称 |
2-METHYL PIPERAZINE DERIVATIVES FOR TREATMENT OF SEROTONIN-RELATED DISORDERS |
摘要 |
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I). The invention also relates to (2R)-1-(3 -chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride and a process for preparing the same. Another object of the present invention is a compound of the formula (I). Another object of the present invention is a method for the treatment or prophylaxis of a serotonin-related disorder, comprising administering to a subject in need thereof an effective amount of the compound above; as well as the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
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申请公布号 |
CA2723494(A1) |
申请公布日期 |
2003.12.31 |
申请号 |
CA20032723494 |
申请日期 |
2003.06.18 |
申请人 |
BIOVITRUM AB (PUBL) |
发明人 |
CERNERUD, MAGNUS;LUNDSTROEM, HELENA;LOEFSTROEM, CLAES;PELCMAN, MARGIT;FLECK, TOM;PAPTCHIKHINE, ALEXANDER;ANDERSSON, EMMA;NYGREN, ALF |
分类号 |
C07D401/14;A61K31/497;A61P3/04;A61P3/10;C07D401/12 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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