发明名称 ORTHO-SUBSTITUTED BENZOIC ACID DERIVATIVES FOR THE TREATMENTOF INSULIN RESISTANCE
摘要 The present invention provides a compound of formula (I), wherein n is 0, 1 or 2; R1 represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substituted by on e or more fluoro and wherein when n is 2 the substituents R1 may be the same o r different; R2 represents an unbranched C2-7alkyl group; R3 represents H or OCH3; and W represents O or S and pharmaceutically acceptable salts and prodrugs thereof, to processes for preparing such compounds, to their utilit y in treating clinical conditions associated with insulin resistance, to metho ds for their therapeutic use and to pharmaceutical compositions containing them .
申请公布号 CA2490684(A1) 申请公布日期 2003.12.31
申请号 CA20032490684 申请日期 2003.06.17
申请人 ASTRAZENECA AB 发明人 LI, LANNA
分类号 A61P3/04;A61K;A61K31/19;A61K31/192;A61P;A61P3/06;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07C;C07C235/20;C07C323/20;C07C323/62;(IPC1-7):C07C323/62 主分类号 A61P3/04
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