| 发明名称 |
DNA SEQUENCE AND RECOMBINANT PRODUCTION OF THE GRASS POLLEN ALLERGEN PHL P4 |
| 摘要 |
<p>The invention relates to the provision of the gene sequence of the grass pollen main allergen Phl p 4. The invention also includes fragments, novel combinations of partial sequences and point mutants having a hypoallergenic effect. The recombinant DNA molecules and the derived polypeptides, fragment s, novel combinations of partial sequences and variants can be used for the therapy of pollen-allergy diseases. The recombinantly produced proteins can be used for in vitroand in vivodiagnosis of pollen allergies.</p> |
| 申请公布号 |
CA2491038(A1) |
申请公布日期 |
2003.12.31 |
| 申请号 |
CA20032491038 |
申请日期 |
2003.06.11 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
FIEBIG, HELMUT;PETERSEN, ARND;BECKER, WOLF-MEINHARD;CROMWELL, OLIVER;SUCK, ROLAND;NANDY, ANDREAS |
| 分类号 |
C12N15/29;A61K38/00;A61K38/16;A61K39/36;A61K48/00;C07K14/415;C12N15/11;C12N15/63;C12P21/00;G01N33/68;(IPC1-7):C12N15/29;A61P37/08;A61K39/35 |
主分类号 |
C12N15/29 |
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