| 发明名称 |
Method of targeting pharmaceuticals to motor neurons |
| 摘要 |
A method of targeting therapeutic molecules to motor neurons is disclosed. In one embodiment, this method comprises the steps of (a) synthesizing a prodrug comprising a therapeutic molecule covalently bound to a polymeric delivery vehicle, and (b) conjugating the prodrug to a botulinum neurotoxin heavy chain.
|
| 申请公布号 |
US6670322(B2) |
申请公布日期 |
2003.12.30 |
| 申请号 |
US20010870262 |
申请日期 |
2001.05.30 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
GOODNOUGH MICHAEL C.;JOHNSON ERIC A.;TEPP WILLIAM H.;MALIZIO CARL J. |
| 分类号 |
A61K47/48;(IPC1-7):A61K47/48;A61K39/08;C07K17/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
