ISOCHROMAN COMPOUNDS AND THEIR PRODUCTION PROCESS

摘要

This invention relates to the isochroman compound of formula (I) (see above formula) and its pharmaceutically acceptable salts, which are useful as an amyloid aggregation inhibitor and for treating Alzheimer's disease. This invention also relates to processes for producing the isochroman compound, which comprises cultivating Penicillium simplicissimum FERM BP-6357 and then isolating the isochrom an compound from the fermentation broth. The present invention also relates to a pharmaceutical composition comprising the isochroman compound.