| 摘要 |
FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to derivatives of benzothiepine-1,1-dioxides and their additive salts with acids of the formula (I): wherein R1 means methyl, ethyl, propyl, butyl; R2 is hydrogen atom, OH; R3 is a saccharide residue being saccharide residue is mono- or multi-substituted if necessary with one or more protective group for saccharides; R4 means methyl, ethyl, propyl, butyl; R5 means methyl, ethyl, propyl, butyl; Z means (C=O)n-C1-C16-alkyl-NH-, covalent bond; n = 1. Compounds can be used as hypolipidemic agents. Invention describes also method for preparing these compounds and a medicinal agent based on thereof. EFFECT: improved preparing method, valuable medicinal properties of compounds. 13 cl, 1 tbl, 13 ex |
