发明名称 Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds
摘要 The present invention concerns new amino alcohol derivatives, a process for their production as well as pharmaceutical preparations and reagents which contain these substances. The invention concerns pharmaceutical agents of the general formula I in which A denotes hydrogen, a group NR1R2, a group NR1(CH2)pNR3R4, a group (C=NH)NH2 or a pyridinyl residue, B and D are the same or different and each denotes a bond, a C1 to C6 alkylene residue or a group NR5-C2 to C6-alkylene, C denotes piperidinediyl or piperazinediyl, W and X are the same or different and each denotes a bond or a carbonyl group, Y and Z are the same or different and each denotes a saturated or unsaturated hydrocarbon residue with 7 to 24 carbon atoms, R1 to R5are the same or different and each represents hydrogen or a C1 to C6 alkyl residue, m is an integer 0, 1 or 2 and if m equals 2 C can also independently of one another be piperidinediyl or piperazinediyl, n and o are the same or different and each denotes the integers 2, 3 or 4 and p denotes an integer from 2 to 6 as well as physiologically tolerated salts thereof, provided that hydrazine derivatives are not included and that m cannot be 0 if A denotes hydrogen or a group (C=NH)NH2 and B and D being the same or different represent a bond or an alkylene residue.
申请公布号 US2003236266(A1) 申请公布日期 2003.12.25
申请号 US20020059207 申请日期 2002.01.31
申请人 ROCHE DIAGNOSTICS GMBH 发明人 FRIEBE WALTER-GUNAR;DIMOUDIS NIKOLAOS;MICHAELIS UWE;KNIPP BERNHARD
分类号 A61K48/00;C07C219/06;C07D211/26;C07D295/13;(IPC1-7):A61K31/496;A61K31/495;A61K31/454;A61K31/445 主分类号 A61K48/00
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