A METHOD FOR SIMULTANEOUS PRODUCTION OF MULTIPLE PROTEINS; VECTORS AND CELLS FOR USE THEREIN

摘要

The present invention relates to a method for improving expression of two or more proteins in a (host) cell. The method is suited for production of for example recombinant antibodies that can be used in a pharmaceutical preparation or as a diagnostic tool. In one embodiment, the invention provid es a method for obtaining a cell which expresses two or more proteins comprisin g providing said cell with two or more protein expression units encoding said two or more proteins, characterised in that at least two of said protein expression units comprise at least one STAR sequence wherin said STAR sequen ce protects said transgenes from the effect of gene silencing.