| 发明名称 |
1-((5-ARYL-1,2,4-OXADIAZOL-3-YL)BENZYL)AZETIDINE-3-CARBOXYLATES AND 1-((5-ARYL-1,2,4-OXADIAZOL-3-YL)BENZYL)PYRROLIDINE-3-CARBOXYLATES ASEDG RECEPTOR AGONISTS |
| 摘要 |
The present invention encompasses compounds of Formula I: as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions a nd methods of use are included.
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| 申请公布号 |
CA2488117(A1) |
申请公布日期 |
2003.12.24 |
| 申请号 |
CA20032488117 |
申请日期 |
2003.06.16 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
HALE, JEFFREY J.;LI, ZHEN;MILLS, SANDER G.;LYNCH, CHRISTOPHER L.;NEWAY, WILLIAM E., III;CHEN, WEIRONG |
| 分类号 |
A61K31/4245;A61K31/454;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P7/06;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P17/14;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/06;A61P25/28;A61P27/02;A61P27/12;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D413/02;C07D413/10;C07D413/14;(IPC1-7):C07D413/10 |
主分类号 |
A61K31/4245 |
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