A controlled-release drug composition characterized by comprising a composition (A) that contains pitavastatin or its salt or ester and initiates release thereof at least in the stomach and an enteric composition (B) that contains pitavastatin or its salt or ester. The use of this controlled-release drug composition leads to prolonged appropriate maintenance, starting just after administration, of the blood level of pitavastatin, so that safe and highly effective reduction of the blood cholesterol level can be realized.
