| 发明名称 |
OX40 (=CD134) RECEPTOR AGONISTIC AND THERAPEUTIC USE |
| 摘要 |
<p>The present invention provides binding molecules, such as human binding molecules, that bind to and stimulate the human 0X40-receptor. The invention also provides nucleic acids encoding such binding molecules. Methods for producing such binding molecules are also provided by the present invention. Said binding molecules and nucleic acids are useful in the stimulation of human T-cells, and can be used to enhance antigen-specific immune responses.</p> |
| 申请公布号 |
CA2489004(A1) |
申请公布日期 |
2003.12.24 |
| 申请号 |
CA20032489004 |
申请日期 |
2003.06.13 |
| 申请人 |
CRUCELL HOLLAND B.V. |
发明人 |
BAKKER, ALEXANDER BERTHOLD HENDRIK;BAKKER, ADRIANUS QUIRINUS;MEESTER-ROOD, PAULINE MARIE LOUISE |
| 分类号 |
A61K31/00;A61K49/00;A61K51/10;A61P31/00;A61P35/00;A61P37/04;C07K16/28;G01N33/564;G01N33/68;(IPC1-7):C12N15/13;A61K48/00;C12P21/08;A61K39/395;A61K47/48;G01N33/566;C12Q1/68;A61K31/708 |
主分类号 |
A61K31/00 |
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