摘要 |
<p>Based on the unexpected association of a polymorphism in the gene coding for HSD11B1 with increased genetic risk for a neurodegenerative disease, in particular Alzheimer's disease, the present invention provides a method of diagnosing or prognosticating such a disease, or determining the propensity or predisposition of a subject to develop such a disease. The method comprises detecting the presence or absence of a single nucleotide polymorphism in the gene coding for HSD11B1.</p> |