| 发明名称 |
GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS |
| 摘要 |
Novel guanidine compounds having the formula (I) in which Rl, R2 and R4 are as defined, are effective as sodium channel blockers in neuronal mammalian cells and as anesthetics and/or analgesics, particularly local spinal and/or epidural anesthetics, for alleviation of neuropathic pain, for providing a neuroprotective effect, and for producing anticonvulsant effects. |
| 申请公布号 |
WO03105779(A2) |
申请公布日期 |
2003.12.24 |
| 申请号 |
WO2003US19127 |
申请日期 |
2003.06.16 |
| 申请人 |
TAKTIX CORPORATION |
发明人 |
DRASNER, KENNETH;WEBER, KEVIN, T. |
| 分类号 |
A61K31/4184;A61K31/454;A61K31/5377;A61P9/10;A61P23/00;A61P23/02;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P43/00;C07D235/30;C07D405/06;C07D409/06 |
主分类号 |
A61K31/4184 |
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