发明名称 |
2,5-DISUBSTITUTED 3-MERCAPTOPENTANOIC ACID |
摘要 |
The present invention concerns compounds of formula (I), and pharmaceutically acceptable salts or solvates thereof, or solvates of such salts, which compounds inhibit carboxypeptidase U and thus can be used in the prevention and treatment of diseases where inhibition of carboxypeptidase U is beneficial. In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt or solvate thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above.
|
申请公布号 |
WO03106420(A1) |
申请公布日期 |
2003.12.24 |
申请号 |
WO2003SE00970 |
申请日期 |
2003.06.10 |
申请人 |
ASTRAZENECA AB;POLLA, MAGNUS |
发明人 |
POLLA, MAGNUS |
分类号 |
C07D277/20;A61K31/426;A61K31/427;A61K31/435;A61K31/439;A61K31/44;A61K31/506;A61P1/16;A61P7/02;A61P9/10;A61P11/00;A61P17/00;A61P29/00;A61P35/00;A61P43/00;C07D211/34;C07D213/73;C07D213/74;C07D213/76;C07D221/22;C07D277/40;C07D277/42;C07D401/06;C07D401/12;C07D405/06;C07D405/12;C07D409/06;C07D409/12;(IPC1-7):C07D213/74;C07D227/40 |
主分类号 |
C07D277/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|