发明名称 |
Vaccines and immunotherapeutics derived from the human immunodeficiency virus (HIV) trans-activator of transcription protein for the treatment and prevention of HIV disease |
摘要 |
Anti-lentivirus vaccines and immunotherapeutics and methods for preparing and using same are disclosed. The vaccines and immunotherapeutics are produced using non-immunosuppressive lentivirus trans-activator of transcription (Tat) proteins. An associated in vitro ultra-sensitive macrophage Tat bioassay is disclosed for assessing the immunosuppressive qualities of the lentivirus Tat preparations of the present invention. Additionally, a related long-term T4 cell propagation system for characterizing lentivirus Tat is also disclosed. The present invention has additional utility in the treatment and prevention of AIDS.
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申请公布号 |
US6667151(B1) |
申请公布日期 |
2003.12.23 |
申请号 |
US20000636057 |
申请日期 |
2000.08.10 |
申请人 |
INIST, INC. |
发明人 |
COHEN DAVID I. |
分类号 |
A61K39/00;A61K39/21;A61K39/39;A61P31/18;C07K14/16;(IPC1-7):C12Q1/70 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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