发明名称 |
Organoboron derivatives and process for coupling organic compounds |
摘要 |
A process for covalently coupling organic compounds which comprises: reacting an olefinic compound having at least one carbon to carbon double bond or an acetylenic compound having at least one carbon to carbon triple bond with a diboron derivative in the presence of a Group 8-11 metal catalyst to form an organoboron intermediate having an organoboronate residue on at least one carbon atom of the respective double or triple bond; and reacting the organoboron intermediate with an organic compound having a halogen or halogen-like substituent at a coupling position in the presence of a Group 8-11 metal catalyst and a suitable base, whereby the olefinic or acetylenic compound is coupled to the organic compound via a direct bond between the carbon atom having the organoboronate residue and the coupling position. Also described is a process for preparing an organoboron derivative, which comprises reacting an olefinic compound having a leaving group in at the allylic position with a diboron derivative in the presence of a Group 8-11 metal catalyst such that the leaving group is replaced with an organoboronate residue. The invention further relates to organoboron intermediates and their preparation.
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申请公布号 |
NZ510903(A) |
申请公布日期 |
2003.12.19 |
申请号 |
NZ19990510903 |
申请日期 |
1999.10.14 |
申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCHORGANISATION |
发明人 |
MARCUCCIO, SEBASTION MARIO;RODOPOULOS, MARY;WEIGOLD,HELMUT;OSVATH, PETER |
分类号 |
C07B61/00;C07B37/04;C07F5/02;C07F5/04;(IPC1-7):C07F5/04;C07B37/02 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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