SIGNALS AND MOLECULAR SPECIES INVOLVED IN SENESCENCE

摘要

The present invention relates to (a) a method for detecting a senescent cell, which comprises measuring a relative alteration to young cell in a signal or molecular species involved in signal transduction; (b) a method; and (c) a composition for modulating cellular senescence comprising treating a senescent cell with the effective amount of an inhibitor of adenylyl cyclase or an inhibitor of protein kinase A.