发明名称 |
REMEDIES FOR NEURODEGENERATIVE DISEASES |
摘要 |
Preventive and/or therapeutic drugs for neuro- degenerative diseases including Alzheimer's disease, which contain as the active ingredient substances selected from the group consisting of compounds represented by the general formula (I), pharmacologically acceptable salts thereof, and hydrates and solvates of both: (I) wherein A is hydrogen or acetyl; E is 2,5- or 3,5-disubstituted phenyl or an optionally substituted monocyclic or fused -polycyclic heteroaryl group (exclusive of (1) fused-polycyclic heteroaryl whose benzene ring is bonded directly to the -CONH- group, (2) unsubstituted thiazol-2-yl, and (3) unsubstituted benzothiazol-2-yl); and Z is arene which may have a substituent in addition to the groups represented by the general formulae: -O-A (wherein A is as defined above) and -CONH-E (wherein E is as defined above) or heteroarene which may have a substituent in addition to the groups represented by the general formulae: -O-A (wherein A is as defined above) and -CONH-E (wherein E is as defined above).
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申请公布号 |
WO03103657(A1) |
申请公布日期 |
2003.12.18 |
申请号 |
WO2003JP07128 |
申请日期 |
2003.06.05 |
申请人 |
INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC.;MUTO, SUSUMU;ITAI, AKIKO |
发明人 |
MUTO, SUSUMU;ITAI, AKIKO |
分类号 |
A61K31/167;A61K31/17;A61K31/18;A61K31/235;A61K31/277;A61K31/381;A61K31/40;A61K31/402;A61K31/404;A61K31/415;A61K31/4164;A61K31/42;A61K31/421;A61K31/422;A61K31/426;A61K31/427;A61K31/433;A61K31/437;A61K31/44;A61K31/4406;A61K31/4418;A61K31/445;A61K31/451;A61K31/454;A61K31/47;A61K31/496;A61K31/498;A61K31/505;A61K31/695;(IPC1-7):A61K31/167;A61K31/416;A61K31/440;A61K31/441;A61K31/537 |
主分类号 |
A61K31/167 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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