| 发明名称 |
4-(ARYL OR HETEROARYL) -2-BUTYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANS |
| 摘要 |
A compound of Formula (IA) or Formula (IB) wherein R1, R2, R3, R4, R5, R6, R 7 and R8 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor functio n or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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| 申请公布号 |
CA2486491(A1) |
申请公布日期 |
2003.12.18 |
| 申请号 |
CA20032486491 |
申请日期 |
2003.05.29 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
RAZAVI, HOSSEIN;KIRRANE, THOMAS M.;PROUDFOOT, JOHN ROBERT;THOMSON, DAVID;KUZMICH, DANIEL |
| 分类号 |
A61K31/4045;A61K31/4184;A61K31/437;A61K31/44;A61K31/4402;A61K31/443;A61K31/4439;A61K31/47;A61P1/00;A61P1/16;A61P3/04;A61P3/10;A61P5/00;A61P7/00;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P13/00;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P19/08;A61P25/00;A61P25/04;A61P25/28;A61P27/02;A61P27/06;A61P27/16;A61P29/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D209/14;C07D213/38;C07D213/61;C07D215/12;C07D215/14;C07D215/18;C07D235/10;C07D235/14;C07D401/06;C07D405/06;C07D471/04;(IPC1-7):C07D471/04;A61K31/404;A61K31/407;A61K31/418;A61K31/440 |
主分类号 |
A61K31/4045 |
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