摘要 |
<p>The invention provides methods for preventing or delaying the development of cancer by administering free radical-generating agents to a subject. Representative free radical-generating agents include endoperoxide compounds, such as endoperoxides bearing sesquiterpene compounds such as artemisinin and its analogs, arteflene and its analogs, 1, 2, 4-trioxanes and 1, 2, 4, 5-tetraoxanes. Intracellular iron concentrations may be enhanced by the administration of iron salts or complexes.</p> |