发明名称 ANTISENSE OLIGONUCLEOTIDES AND METHODS TO INDUCE TUMOR CELL DEATH
摘要 This invention relates to the inhibition and down-regulation of survivin expression. The invention provides methods and antisense oligonucleotides for inhibiting or down-regulating survivin expression in cells and promoting apoptosis and cell necrosis.
申请公布号 WO03027244(A3) 申请公布日期 2003.12.18
申请号 WO2002US30276 申请日期 2002.09.24
申请人 HYBRIDON, INC.;KANDIMALLA, EKAMBAR, M.;AGRAWAL, SUDHIR;SHANKAR, SAI, LATHA;SHAFIT-ZAGARDO, BRIDGET;MANI, SRIDHAR 发明人 KANDIMALLA, EKAMBAR, M.;AGRAWAL, SUDHIR;SHANKAR, SAI, LATHA;SHAFIT-ZAGARDO, BRIDGET;MANI, SRIDHAR
分类号 C12N15/09;A61K31/7125;A61K38/00;C12N5/02;C12N15/113 主分类号 C12N15/09
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