The present invention relates to the field of molecular biology and medicine. It particularly relates to methods and means for interfering with the formation of a neointima/scar and/or a plaque. The invention provides a method for interfering with the formation of a neointima/scar and/or a plaque in a blood vessel comprising providing a ligand capable of modulating Toll-like receptor activity of adventitial cells.
申请公布号
WO03030885(A3)
申请公布日期
2003.12.18
申请号
WO2002NL00644
申请日期
2002.10.10
申请人
UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITEIT UTRECHT;DE KLEIJN, DOMINICUS, PASCHALIS, VICTOR;PASTERKAMP, GERARD
发明人
DE KLEIJN, DOMINICUS, PASCHALIS, VICTOR;PASTERKAMP, GERARD