The present invention is directed to an improved method to detect and monitor a subject having cystic fibrosis (CF) by employing a murine anti-NCA 90 monoclonal antibody Fab' fragment and <99m>-technetium. It is further directed to a simple, noninvasive, and effective test that can assess neutrophil delivery to the lower airways of patients with CF and other neutrophil-mediated lung diseases.
申请公布号
WO03103724(A1)
申请公布日期
2003.12.18
申请号
WO2003GB02408
申请日期
2003.06.03
申请人
IMMUNOMEDICS, INC.;MCCALL, JOHN, DOUGLAS;SODEE, BRUCE;KONSTAN, MICHAEL;GOLDENBERG, DAVID, M.
发明人
SODEE, BRUCE;KONSTAN, MICHAEL;GOLDENBERG, DAVID, M.