| 发明名称 |
METHODS FOR BLOCKING ADIPOCYTE DIFFERENTIATION AND TRIGLYCERIDE ACCUMULATION WITH G-ALPHA-I3 INHIBITORS |
| 摘要 |
Methods for blocking adipocyte differentiation and triglyceride accumulation with inhibitors of G-alpha-i3 are provided. G-alpha-i3 inhibitors of the present invention include small molecules, antibodies, peptides (including dominant negative peptides) and antisense compounds, including ribozymes, inhibitory RNA molecules including siRNA molecules and antisense oligonucleotides.
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| 申请公布号 |
WO03104494(A1) |
申请公布日期 |
2003.12.18 |
| 申请号 |
WO2003US18312 |
申请日期 |
2003.06.10 |
| 申请人 |
ISIS PHARMACEUTICALS, INC.;MARCUSSON, ERIC, G.;DEAN, NICHOLAS, M. |
发明人 |
MARCUSSON, ERIC, G.;DEAN, NICHOLAS, M. |
| 分类号 |
A61K38/00;C12N15/113;(IPC1-7):C12Q1/68 |
主分类号 |
A61K38/00 |
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