INHIBITORS OF THE GPIB -VWF INTERACTION, THEIR PREPARATION AND USE

摘要

The present invention relates to compounds of the formula (I); in which R1, R2, A, B, D, E, n, m or o have the meanings indicated below. The compounds of the formula (I) are valuable pharmacologically active compounds. They are reversible inhibitors of the interaction between the plasma protein von Willebrand factor (vWF) and the blood platelet receptor glycoprotein Ib-IX-V complex (GPIb). They exhibit an antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of atherothrombotic diseases.