| 摘要 |
Emulsion and microemulsion aerosol formulations in a HFA propellant system include a medicament, one or more surfactant, optionally a cosolvent and water. Emulsion formulations are based on 0.1-% w/w surfactant and 1-10% w/w water. Microemulsion formulations are based on 1-20% w/w surfactant, 1-30% w/w cosolvent and 1-10% w/w water. Preferred surfactant are Span 85, AOT and their blends, synperonics and alkylpolyglucosides (APGs) The preferred cosolvent is ethanol.
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| 申请人 |
CHIESI FARMACEUTICI S.P.A.;MEAKIN, BRIAN, JOHN;LEWIS, DAVID, ANDREW;BERRILL, SUSAN, ANN;DAVIES, REBECCA, JAYNE |
发明人 |
MEAKIN, BRIAN, JOHN;LEWIS, DAVID, ANDREW;BERRILL, SUSAN, ANN;DAVIES, REBECCA, JAYNE |
