发明名称 Antisense modulation of amyloid beta protein precursor expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of amyloid beta protein precursor. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding amyloid beta protein precursor. Methods of using these compounds for modulation of amyloid beta protein precursor expression and for treatment of diseases associated with expression of amyloid beta protein precursor are provided.
申请公布号 US2003232435(A1) 申请公布日期 2003.12.18
申请号 US20020173208 申请日期 2002.06.14
申请人 ISIS PHARMACEUTICALS INC. 发明人 DOBIE KENNETH W.
分类号 A61K38/00;A61K48/00;C12N15/113;(IPC1-7):A61K48/00;C07H21/04;C12N5/00 主分类号 A61K38/00
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