摘要 |
<p>A sensor for electrochemically or optically determining a desired species, the sensor comprising at least one electrode or optical path, wherein the electrode or optical path is modified for specific accumulation of the desired species, by means of a modifying agent which is adapted to selectively and substantially reversibly bind the species to be detected and to release the species at a characteristic voltage or give an absorbance measurement at a characteristic optical wavelength, and wherein the modifying agent is associated with at least part of the surface of the electrode or optical path by physical or chemical anchoring. A method of fabricating and using such a sensor, particularly in harsh media such as whole blood and other body fluids, brackish water, industrial environments and the like.</p> |