发明名称 |
EMULSION FORMULATIONS FOR THE DELIVERY OF NUCLEIC ACIDS TO CELLS |
摘要 |
<p>New emulsion and micelle formulations are described as are complexes of these formulations with biologically active substances. The novel formulations are different from cationic lipid vectors such as cationic liposomes in that the complexes formed between biologically active substances and the emulsion and micellar formulations of this invention are physically stable and their transfection activity is resistant to the presence of serum. These novel formulations are disclosed to be useful in areas such as gene therapy or vaccine delivery.</p> |
申请公布号 |
EP0852490(B1) |
申请公布日期 |
2003.12.17 |
申请号 |
EP19960933899 |
申请日期 |
1996.09.26 |
申请人 |
UNIVERSITY OF PITTSBURGH |
发明人 |
LIU, DEXI;LIU, FENG;YANG, JING-PING;HUANG, LEAF |
分类号 |
A61K9/107;A61K31/70;A61K31/7088;A61K38/00;A61K39/00;A61K47/18;A61K47/24;A61K48/00;(IPC1-7):A61K9/107 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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