| 摘要 |
A therapeutic or preventive agent for liver diseases, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt:wherein X is a -CW<1>R<1 >group, a -COCOR<2 >group, a -CW<1>NHCOR<2 >group, a -C(=W<1>)W<2>R<3 >group or a -CW<1>N(R<4>)R<5 >group; Y is an alkyl group, a -CW<3>R<6 >group, a -COCOR<7 >group, a -NHCOR<7 >group, a -C(=W<3>)W<4>R<8 >group, a -(NH)mSO2R<9 >group, a -(NH)mSO2OR<10 >group or a -(NH)mSO2N(R<11>)R<12 >group; each of R<1>, R<6 >and R<9 >is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R<2 >and R<7 >is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R<3>, R<8 >and R<10 >is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R<4>, R<5>, R<11 >and R<12 >is an alkyl group; each of W<1>, W<2>, W<3 >and W<4 >is an oxygen atom or a sulfur atom; and m is 0 or 1, is provided.
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