Human neuronal nicotinic acetylcholine receptor & subunit methods employing same

摘要

DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing the DNA, methods for producing alpha and beta subunits and isolated or substantially pure alpha4, alpha7 and beta4 subunits are provided. In addition, cells that expresses these subunits singly or combination with other subunits of nicotinic acetylcholine receptors and methods using the cells are provided.